Drugs discovered by the pharmaceutical industry over the past 100 years have dramatically changed the practice of medicine and impacted many aspects of culture. Traditionally, drug discovery relied on natural products as the primary source of new drug entities but was later shifted toward high-throughput synthesis and combinatorial chemistry-based development. New technologies such as ultra-high-throughput drug screening and artificial intelligence are heavily employed to reduce the cost and the time of early drug discovery, but they remain relatively unchanged. With the advent of modern molecular biology methods and based on knowledge of the human genome, drug discovery has now largely changed into a hypothesis-driven target-based approach. This development was paralleled by significant environmental changes in the pharmaceutical industry.
New paradigms in drug discovery and development rely on new technologies. These include DNA sequencers and a wide variety of new tools for gathering, analyzing, and disseminating genetic and genomic information. Advanced laboratories are now using robotics for automated screening to increase the overall speed of drug discovery. In addition, Magnetic Resonance Mass Spectrometry (MRMS) is a newfound instrument that provides an extra layer of confidence in screening for weak interactions of fragments. Further, major pharma companies have started adopting various strategies to integrate AI into their drug discovery process by hiring AI experts and data analysts. Several more pharma companies also implement machine learning-based deep learning technology to transform the small molecule research field and new biologics.
This edition of Pharma Tech Outlook brings you the companies providing cutting-edge drug discovery and development tech solutions and services. We hope the exhaustive information presented in the edition comes in handy for you to choose the right partner. In our selection, we looked at companies’ ability to identify client requirements, develop a strategic approach, and provide support and customization through their offerings.
We present to you Pharma Tech Outlook’s “Top 10 Drug Discovery and Development Companies in Europe - 2021.”
